Be good to yourself. You're the only you you have.
Detox in place: Yes, you can do this at home. Announce to those within shouting distance that you'll be forgoing your usual chores, duties, and routines. You'll be resting, relaxing, taking time for yourself, eating lightly, thinking good thoughts -- devoting the weekend to self-care. Therefore, everyone can make their own bologna sandwiches and pull their own underwear out of the dryer.
Give your digestive system a break. Forgo -- as much as possible -- meat, alcohol, sugar, caffeine. Giving up that first cup of coffee would feel like torture to me, and this weekend is not about deprivation, so I'll have my morning java, but will make conscious choices. For me that means no processed foods or heavy meals, but throughout the day enjoying my favorite grapefruit, small servings of granola and yogurt, vegetable juices, a little decaf tea in the evening.
Give your connectedness a break. The 24/7 news cycle will spin quite adequately without you. Skim the paper if you must, but that's it. No cable news. If you have a favorite show or light movie in mind -- of course, enjoy it. But don't let the television or radio provide constant background noise. Revel in the quiet. And eschew Facebook, Twitter, Pinterest, Snapchat . . .. If you must communicate with loved ones via e-mail or social media, do so briefly and efficiently. For 48 hours, be your own best friend.
Give your emotions a break. We're all carrying some worrisome burden. Put it down for the weekend. My mother would advise me, when things were very bad, to "close the book and put in on the shelf." You're not forgetting your trouble, not pretending it doesn't exist: Just briefly setting it aside. On Monday, stronger and refreshed, you may pick it up where you left off if you must.
Move and appreciate your body. Take a brisk walk around the neighborhood. Play some music from the 80s and dance in your kitchen. Enjoy a hot bath and afterward, smooth wonderfully scented lotion on your skin. Rest. Breathe deeply. Your body works hard for you. Give it its due.
Create something. Write a poem, a story, a song. Paint a picture. Make a collage (below, a birthday collage I made for a friend). Devote a few hours this weekend to reveling in simple, unadulterated creative joy.